IL-1α Antibody, anti-human
Clone:
364-3B3-14
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
ICFC
Alternative names:
IL-1 alpha, H-1, LAF, BAF, OAF, PIF

Specifications for IL-1α Antibody, anti-human

Overview

Clone 364-3B3-14 recognizes the human IL-1α antigen, a cytokine of the interleukin-1 (IL-1) family. IL-1α is produced mainly by activated macrophages, neutrophils, as well as epithelial and endothelial cells. IL-1 is responsible for the production of inflammation as well as the promotion of fever and sepsis. IL-1α interacts with TNF and promote fever and inflammation. The 364-3B3-14 antibody does not cross-react with human IL-1β.

Alternative names

IL-1 alpha, H-1, LAF, BAF, OAF, PIF

Detailed product information

Technical specifications

Clone364-3B3-14
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman, non-human primate
Cross-reactivity
rhesus monkey (
Macaca mulatta
)
AntigenIL-1α
Alternative names of antigenIL-1 alpha, H-1, LAF, BAF, OAF, PIF
Molecular mass of antigen [kDa]18
Distribution of antigenepithelial cells, endothelial cells, macrophages, neutrophils
Entrez Gene ID3552
RRIDAB_2652398, AB_2652399, AB_2652397, AB_2652396

Resources for IL-1α Antibody, anti-human

Certificates

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References for IL-1α Antibody, anti-human

Publications

  1. March, C. J. et al. (1985) Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs. Nature 315(6021): 641-647
  2. Nicklin, M. J. et al. (1994) A physical map of the region encompassing the human interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist genes. Genomics 19(2): 382-384
  3. Satoh, H. et al. (1994) Characterization of anti-IL-1α autoantibodies in the sera from healthy humans. Immunopharmacology 27(2): 107-118

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