Clone:
REA381
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
IFNGR2, IFGR2, Ifgt, AF-1, IFNGRB, IFNGT1, IFNγ R2, IFNγ Rβ

Specifications for IFN-γR β chain Antibody, anti-mouse, REAfinity™

Overview

Clone REA381 recognizes the mouse IFN-γ receptor β chain antigen, a type 1 transmembrane protein also known as IFN-γ accessory factor 1 (AF-1). The IFN-γR β chain pairs with CD119 to form the IFN-γ receptor. It is expressed at low levels on T and B cells, NK cells, monocytes, macrophages, and fibroblasts. IFN-γ induces several biologic effects in target cells, including antiviral and antiproliferative responses, expression of major histocompatibility complex and of Fc receptor genes, and immunoglobulin class switching.
Additional information: Clone REA381 displays negligible binding to Fc receptors.

Alternative names

IFNGR2, IFGR2, Ifgt, AF-1, IFNGRB, IFNGT1, IFNγ R2, IFNγ Rβ

Detailed product information

Technical specifications

CloneREA381
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenIFN-γR β chain
Alternative names of antigenIFNGR2, IFGR2, Ifgt, AF-1, IFNGRB, IFNGT1, IFNγ R2, IFNγ Rβ
Molecular mass of antigen [kDa]38
Distribution of antigenB cells, T cells, NK cells, macrophages, monocytes, fibroblasts
Entrez Gene ID15980
RRIDAB_2652252, AB_2652253, AB_2652254, AB_2652255, AB_2652256, AB_2652257, AB_2652258, AB_2652251

Resources for IFN-γR β chain Antibody, anti-mouse, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for IFN-γR β chain Antibody, anti-mouse, REAfinity™

Publications

  1. Marsters, S. A. et al. (1995) Interferon gamma signals via a high-affinity multisubunit receptor complex that contains two types of polypeptide chain. Proc. Natl. Acad. Sci. U.S.A. 92(12): 5401-5405
  2. Hemmi, S. et al. (1994) A novel member of the interferon receptor family complements functionality of the murine interferon gamma receptor in human cells. Cell 76(5): 803-810
  3. Ebensperger, C. et al. (1996) Genomic organization and promoter analysis of the gene ifngr2 encoding the second chain of the mouse interferon-gamma receptor. Scand. J. Immunol. 44(6): 599-606

Related products for
IFN-γR β chain Antibody, anti-mouse, REAfinity™

3 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?