Clone:
REA1109
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
ICFC
Alternative names:
CTLA3, HuTPS, TSP-1, GZMA, CTLA-3, Mtsp-1, Fragmentin-1

Specifications for Granzyme A Antibody, anti-mouse, REAfinity™

Overview

Clone REA1109 recognizes the mouse Granzyme A, which is located in CD8+ T cells and in normal lymphoid tissues such as thymus and spleen. Granzyme A belongs to the serine protease family, which is involved in cell lysis mediated by cytotoxic T lymphocytes (CTLs) and NK cells. Also known as granule enzymes, granzymes comprise majority of the mass of cytolytic granules in cytotoxic T lymphocytes (CTLs) and NK cells.
Additional information: Clone REA1109 displays negligible binding to Fc receptors.

Alternative names

CTLA3, HuTPS, TSP-1, GZMA, CTLA-3, Mtsp-1, Fragmentin-1

Detailed product information

Technical specifications

CloneREA1109
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenGranzyme A
Alternative names of antigenCTLA3, HuTPS, TSP-1, GZMA, CTLA-3, Mtsp-1, Fragmentin-1
Molecular mass of antigen [kDa]26
Distribution of antigenNK cells, T cells, CD8+ T cells
Entrez Gene ID14938
RRIDAB_2876983, AB_2877000, AB_2877001, AB_2876940, AB_2876941, AB_2876982

Resources for Granzyme A Antibody, anti-mouse, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for Granzyme A Antibody, anti-mouse, REAfinity™

Publications

  1. Simon, M.M. et al. (1986) Purification and characterization of a T cell specific serine proteinase (TSP-1) from cloned cytolytic T lymphocytes. EMBO J. 5(12): 3267-3274
  2. Trapani, J. A. (2001) Granzymes: a family of lymphocyte granule serine proteases. Genome Biol. 2(12): 3014.1-3014.7

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