Clone:
REA1072
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
ICFC, MICS, IF, IHC
Alternative names:
LGALS3, CBP35, GAL3, GALBP, L31, LGALS2, Mac-2

Specifications for Galectin-3 Antibody, anti-human/mouse, REAfinity™

Overview

Clone REA1072 recognizes mouse and human galectin-3, which is a 32 kDa protein belonging to the beta-galactoside-binding animal lectin family. Galectin-3, also known as Mac-2, has an IgE-binding activity and is localized in Kupffer cells, macrophages, human peripheral blood monocytes, and murine activated T cells. An upregulated expression of galectin-3 is observed during cell proliferation, differentiation, and inflammation.
Additional information: Clone REA1072 displays negligible binding to Fc receptors.

Alternative names

LGALS3, CBP35, GAL3, GALBP, L31, LGALS2, Mac-2

Detailed product information

Technical specifications

CloneREA1072
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (I), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman, mouse
AntigenGalectin-3
Alternative names of antigenLGALS3, CBP35, GAL3, GALBP, L31, LGALS2, Mac-2
Molecular mass of antigen [kDa]26(separately shown for human and mouse/rat)
Distribution of antigenmacrophages, monocytes, T cells
Entrez Gene ID16854, 3958
RRIDAB_2733579, AB_2733703, AB_2733704, AB_2733294, AB_2733295, AB_2733578

Resources for Galectin-3 Antibody, anti-human/mouse, REAfinity™

Certificates

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References for Galectin-3 Antibody, anti-human/mouse, REAfinity™

Publications

  1. Springer, T. A. et al. (1981) Monoclonal antibody analysis of complex biological systems. Combination of cell hybridization and immunoadsorbents in a novel cascade procedure and its application to the macrophage cell surface. J. Biol. Chem. 256: 3833-3839
  2. Ho, M. K. and Springer, T. A. et al. (1982) Mac-2, a novel 32,000 Mr mouse macrophage subpopulation-specific antigen defined by monoclonal antibodies. J. Immunol. 128: 1221-1228
  3. Liu, F. T. et al. (1995) Expression and function of galectin-3, a beta-galactoside-binding lectin, in human monocytes and macrophages. Am. J. Pathol. 147(4): 1016-1028
  4. Joo, H. G. et al. (2001) Expression and function of galectin-3, a ß-galactoside-binding protein in activated T lymphocytes. J. Leukoc. Biol. 69: 555-564

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