The T cell receptor (TCR) is a heterodimer composed of two transmembrane glycoprotein chains, α and β. Both chains are members of the Ig superfamily and consist of a constant and a polymorphic variable region. The variable region of the TCRα/β is involved in recognition of antigenic peptides presented by the MHC complex of antigen-presenting cells. The TCRα/β is expressed on the majority of peripheral blood T cells. The Anti-TCRα/β antibody recognizes a common determinant of the TCRα/β-CD3 complex.
The CliniMACS
TCRα/β Product Line consists of murine anti-TCRα/β monoclonal antibodies conjugated to biotin.

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