MACS GMP Recombinant Human GM-CSF

MACS GMP Recombinant Human GM-CSF

Granulocyte-macrophage colony–stimulating factor (GM-CSF) is a hematopoietic growth factor, which is essential for proliferation and development of granulocyte and monocyte/macrophage progenitors.
MACS GMP Recombinant Human GM-CSF is designed for
ex vivo
cell culture processing. No animal- or human-derived materials were used for the manufacture of this product, unless otherwise stated in the respective Certificate of Origin. The product is lyophilized without carrier protein or preservatives.


MACS GMP Products are for research use and
ex vivo
cell culture processing only, and are not intended for human
in vivo
applications. For regulatory status in the USA, please contact your local representative.

Background information

Beside its role as growth factor for granulocyte and monocyte precursors, GM-CSF also functions as a growth factor for erythroid and megakaryocytic precursor cells in conjunction with erythropoietin. GM-CSF is secreted by various cell types including T cells, macrophages, endothelial cells, and fibroblasts in response to inflammatory stimuli and cytokines. In addition, GM-CSF is a potent chemoattractant for neutrophils and eosinophils and enhances the effector functions of neutrophils and macrophages.


MACS GMP Recombinant Human GM-CSF can be used for a variety of applications, including the
ex vivo
generation of human dendritic cells from enriched CD14

Quality statement

MACS GMP Products are manufactured and tested under a quality management system (ISO 13485) and are in compliance with relevant GMP guidelines. They are designed following the recommendations of USP <1043> on ancillary materials.

Biological activity

  • The specific activity is determined by proliferation assay according to Kitamura
    et al.1
    using TF-1 cells provided by the German Resource Centre for Biological Material (DSMZ). The proliferation assay was calibrated with the international standard for human GM-CSF (NIBSC code 88/646) provided by the National Institute for Biological Standards and Control.
  • Specific activity: ≥ 5×
Product options: 2

Product information

Order no.

MACS GMP Recombinant Human GM-CSF

  • E. coli
  • For research use and
    ex vivo
    cell processing only
25 µg
EUR 367,00 

MACS GMP Recombinant Human GM-CSF

  • E. coli
  • For research use and
    ex vivo
    cell processing only
250 µg
EUR 1.612,00 

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