MACS GMP ExpAct Treg Kit

MACS GMP ExpAct Treg Kit

The MACS GMP ExpAct Treg kit has been developed for the efficient expansion of human regulatory T cells for the manufacturing of Treg cells for clinical research.

Disclaimer

MACS GMP Products are for research use and
ex vivo
cell culture processing only, and are not intended for human
in vivo
applications. For regulatory status in the USA, please contact your local representative.

Background information

The MACS GMP ExpAct Treg Kit is based on ExpAct Treg Beads: Large 3.5 µm particles, which are preloaded with CD28 antibodies, anti-biotin antibodies and CD3-Biotin. The kit comes in a convenient format with 1×10
9
ExpAct Treg Beads per vial. An efficient removal of MACS GMP ExpAct Treg Beads can be achieved using the CliniMACS System and the CliniMACS LS Tubing Set.

Applications

The MACS GMP ExpAct Treg Kit has been designed to efficiently expand Treg cells after a CliniMACS CD25 enrichment procedure and to maintain FoxP3 expression. It can be used with rapamycin, which inhibits the expansion of conventional T cells and thereby enhances the proportion of expanded Treg cells in culture.
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Quality statement

MACS GMP Products are manufactured and tested under a quality management system (ISO 13485) and are in compliance with relevant GMP guidelines. They are designed following the recommendations of USP <1043> on ancillary materials.
Product options: 1

Product information

Size
Order no.
Price

MACS GMP ExpAct Treg Kit

  • For research use and
    ex vivo
    cell processing only
2×5 mL
170-076-119
EUR 1.995,00