CD14 antibodies

CD14 antibodies

Clone: REA599
REA599 recognizes the human CD14 antigen. CD14 is part of the functional heteromeric LPS receptor complex comprised of at least CD14, TLR4, and MD-2. It up-regulates cell surface molecules, including adhesion molecules. CD14 is strongly expressed on most human monocytes and macrophages in peripheral blood, other bodily fluids, and in various tissues, such as lymph nodes and spleen. CD14 is weakly expressed on subpopulations of human neutrophils and myeloid dendritic cells. Additional information: Clone REA599 displays negligible binding to Fc receptors.

Applications

Reagent can be used for immunophenotyping by flow cytometry. Abnormal numbers of cells expressing this antigen or aberrant expression levels of the antigen can be expected in some disease states. It is important to understand the normal expression pattern for this antigen and its relationship to expression of other relevant antigens in order to perform appropriate analysis.
Expression of CD14 may be used as aid to diagnostic in the characterization of samples from individuals suspected with hematologic neoplasia.

Alternative Names

LPS R

Technical specifications

  • Antigen: CD14
  • Clone: REA599
  • Isotype: recombinant human IgG1
  • Alternative names of antigen: LPS R
  • Molecular mass of antigen [kDa]: 37
  • Distribution of antigen: B cells, dendritic cells, epithelial cells, granulocytes, Langerhans cells, liver, macrophages, monocytes, osteoclasts, plasma cells
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC
Product options: 1

Product information

Size
Order no.
Price

CD14-APC

  • REA599
  • CE–IVD
for 100
tests
170-078-099
EUR 530,00