Anti-TCRγ/δ antibodies

Anti-TCRγ/δ antibodies

Clone: REA591
REA591 recognizes the human γ/δ T cell receptor (TCR). The T cell receptor is a heterodimeric glycoprotein associated with the CD3 antigen. It consists of a α and a β chain (TCRα/β) or a γ and a δ chain (TCRγ/δ). The γ and δ TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. The γ chain forms either disulfide-linked or non-disulfide–linked heterodimers with the δ-subunit. The γ/δ T cell receptor is present on a subset of T lymphocytes in peripheral blood. TCRγ/δ is involved in the antigen recognition of tumor-associated antigens or bacterial antigens presented by MHC class I molecules.
Additional information: Clone REA591 displays negligible binding to Fc receptors.

Applications

Reagent can be used for immunophenotyping by flow cytometry. Abnormal numbers of cells expressing this antigen or aberrant expression levels of the antigen can be expected in some disease states. It is important to understand the normal expression pattern for this antigen and its relationship to expression of other relevant antigens in order to perform appropriate analysis.
Expression of TCRγ/δ may be used as aid to diagnostic in the characterization of samples from individuals suspected with hematologic neoplasia.

Technical specifications

  • Antigen: TCRγ/δ
  • Clone: REA591
  • Isotype: recombinant human IgG1
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE
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Product information

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Order no.
Price

Anti-TCRγ/δ-PE

  • REA591
  • CE–IVD
for 100
tests
170-078-095
EUR 530,00