Anti-TCRα/β antibodies

Anti-TCRα/β antibodies

Clone: REA652
REA652 recognizes the human α/β T cell receptor (TCR). The T cell receptor is a heterodimer composed of two transmembrane glycoprotein chains, α and β. In 95% of T cells the TCR consists of an α and β chain, whereas in 5% of T cells it has γ and δ chains. α and β chains are members of the Ig superfamily and consist of a constant and a polymorphic variable region. The variable region of the TCRα/β is involved in recognition of antigenic peptides presented by the MHC complex of antigen-presenting cells.
Additional information: Clone REA652 displays negligible binding to Fc receptors.

Applications

Reagent can be used for immunophenotyping by flow cytometry. Abnormal numbers of cells expressing this antigen or aberrant expression levels of the antigen can be expected in some disease states. It is important to understand the normal expression pattern for this antigen and its relationship to expression of other relevant antigens in order to perform appropriate analysis.
Expression of TCRα/β may be used as aid to diagnostic in the characterization of samples from individuals suspected with hematologic neoplasia.

Alternative Names

TCR a/b, IMD7, TCRA, TRAC, TRB

Technical specifications

  • Antigen: TCRα/β
  • Clone: REA652
  • Isotype: recombinant human IgG1
  • Alternative names of antigen: TCR a/b, IMD7, TCRA, TRAC, TRB
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC
  • Brochures and posters

  • Certificates of Analysis (CoA)

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Product options: 2

Product information

Size
Order no.
Price

Anti-TCRα/β-PE

  • REA652
  • CE–IVD
for 100
tests
170-078-093
EUR 530,00 

Anti-TCRα/β-APC

  • REA652
  • CE–IVD
for 100
tests
170-078-094
EUR 420,00