Clone:
VIM3b
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
FC, MICS, IF, IHC, ICC
Alternative names:
ADGRE5, TM7LN1, EMR1

Extended validation for CD97 Antibody, anti-human

Specificity

Epitope competition
In order to compare the epitope specificity of an antibody, the clone being used is compared with other known clones recognizing the same antigen in a competition assay.
Other clonesOverlap in epitope recognition with VIM3b
REA1042++
MEM-180-
Cells were incubated with an excess of purified unconjugated CD97 (VIM3b) antibody followed by staining with fluorochrome-conjugated antibodies of other known clones against the same marker. Based on the fluorescence signal obtained, the clones were identified as recognizing completely overlapping (++), partially overlapping (+), or completely different epitopes (-) of the marker.

Specifications for CD97 Antibody, anti-human

Overview

The VIM3b monoclonal antibody reacts with human CD97, a member of the epidermal growth factor (EGF)-TM7 family of cell surface receptors. CD97 is expressed by various cell types of the hematopoietic system and also on smooth muscle cells. Highest constitutive expression is found on granulocytes and monocytes. Lymphocytes express CD97 at lower level (T and NK cells expressing higher levels than B cells) but on T cells CD97 is upregulated upon activation via CD3 and CD28 or PHA. CD97 is a ligand for CD55 (decay-accelerating factor, DAF) and has been shown to mediate cell adhesion and co-stimulation of T cell proliferation.

Alternative names

ADGRE5, TM7LN1, EMR1

Detailed product information

Technical specifications

CloneVIM3b
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD97
Alternative names of antigenADGRE5, TM7LN1, EMR1
Molecular mass of antigen [kDa]90
Distribution of antigenB cells, dendritic cells, granulocytes, macrophages, monocytes, T cells, B cells, dendritic cells, granulocytes, macrophages, monocytes, T cells, smooth muscle
Entrez Gene ID976
RRIDAB_2659665, AB_2659666, AB_2659667, AB_2659668, AB_2659669, AB_2659670, AB_2659671, AB_2659672, AB_2659673, AB_2889644, AB_2889643

Resources for CD97 Antibody, anti-human

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

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CD97 Antibody, anti-human

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