Clone:
REAL500
Type of antibody:
Releasable antibodies, Primary antibodies, Recombinant antibodies
Applications:
FC
Alternative names:
5H9, MRP-1, Tetraspanin-29 (Tspan-29), TSPAN-29, p24, MIC3, Tspan29, ORF, GIG2

Specifications for CD9 Antibody, anti-human,
REAlease
®

Overview

Clone REAL500 is an antibody fragment derived from the full CD9 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity.
Clone REAL500 recognizes the human CD9 antigen, a 25 kDa cell surface glycoprotein which is also known as tetraspanin-29 (Tspan-29). CD9 belongs to the tetraspanin family of integral proteins, which are characterised by the presence of four conserved transmembrane domains, a small and two large extracellular loops. Expression of CD9 is found on platelets, pre-B cells, fibroblasts, eosinophils, macrophages, basophils, epithelial cells, oocytes, and activated T cells. Further expression is reported on malignant cells and tumor cell lines where CD9 is involved in supressor functions, inhibition of cell invasion and metastasis. CD9 associates with other tetraspanin members, cell adhesion molecules such as EpCAM, integrin subsets, transmembrane proteins (EWI-2 and EWI-F), choline receptors, and G-proteins. Through diverse interactions or via direct stimulation, CD9 influences various cellular functions including cell adhesion, aggregation, migration, clustering of MHC molecules in dendritic cells (DCs) and provides co-stimulatory signal during T cell activation.
The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.

Alternative names

5H9, MRP-1, Tetraspanin-29 (Tspan-29), TSPAN-29, p24, MIC3, Tspan29, ORF, GIG2

Detailed product information

Technical specifications

CloneREAL500
Clonalitymonoclonal
Isotype controlControl Antibody
Hostcell line
Type of antibodyReleasable antibodies, Primary antibodies, Recombinant antibodies
Specieshuman
AntigenCD9
Alternative names of antigen5H9, MRP-1, Tetraspanin-29 (Tspan-29), TSPAN-29, p24, MIC3, Tspan29, ORF, GIG2
Distribution of antigenB cells, fibroblasts, granulocytes, macrophages, platelets, tumor cells, epithelial cells, basophils, eosinophils

Resources for CD9 Antibody, anti-human,
REAlease
®

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

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