Type of antibody:
Primary antibodies
mouse IgG2b

Specifications for CD45RA antibodies


T6D11 recognizes the human CD45RA antigen which is expressed on naive CD4
and CD8
T cells as well as on CD8
effector T cells. CD45RA is also present on subsets of B and NK cells as well as on plasmacytoid dendritic cells. The CD45RA antibody recognizes the 220 kDa isoform of the leukocyte common antigen (LCA), a transmembrane tyrosine phosphatase.

Detailed product information

Technical specifications

Isotypemouse IgG2b
Type of antibodyPrimary antibodies
Molecular mass of antigen [kDa]145
Distribution of antigenB cells, monocytes, NK cells, T cells, thymocytes

Resources for CD45RA antibodies


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References for CD45RA antibodies


  1. Braun, T. et al. (2012)
    Effector CD4
    regulatory T cell (eTreg) distribution is significantly impaired in chronic myelomonocytic leukemia (CMML) and correlates with TET 2 mutational status.
    Blood 120: 2808-2808
  2. Baba, N. et al. (2010)
    Interplay between CD45RA
    regulatory T cells and TNF-α in the regulation of human Tʜ17 differentiation.
    Int. Immunol. 22: 237-244
  3. Cantisan, S. et al. (2010)
    CD45RA expression on HCMV-specific effector memory CD8
    T cells is associated with the duration and intensity of HCMV replication after transplantation.
    Clin. Immunol. 137(1): 81-88
  4. Stelzer, G. T. et al. (1997) U.S.-Canadian consensus recommendations on the immunophenotypic analysis of hematologic neoplasia by flow cytometry: standardization and validation of laboratory procedures. Cytometry 30(5): 214-230
  5. Rothe, G et al. (2012) Consensus protocol for the flow cytometric Immunophenotyping of hematopoietic malignancies. Leukemia 10(5): 877-895
  6. van Dongen, J. J. M. et al. (2012) EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes. Leukemia 26(9): 1908-1975
  7. Clinical and Laboratory Standards Institute (CLSI) (2007) Clinical Flow Cytometric Analysis of Neoplastic Hematolympoid Cells, CLSI document H43-A2 (ISBN 1-56238-635-2). CLSI; Approved Guideline - Second Edition
  8. Clinical and Laboratory Standards Institute (CLSI) (2007) Enumeration of immunologically defined cell populations by flow cytometry, CLSI document H42-A2 (ISBN 1-56238-640-9). CLSI; Approved Guideline - Second Edition
  9. Wood, B. L. et al. (2007) 2006 Bethesda International Consensus recommendations on the immunophenotypic analysis of hematolymphoid neoplasia by flow cytometry: optimal reagents and reporting for the flow cytometric diagnosis of hematopoietic neoplasia. Cytometry B Clin. Cytom. 72: 14-22

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