Clone:
REA977
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC
Alternative names:
Ep-CAM, EGP, KSA, TROP1, Ly74, Tacsd1, Tacstd1, GP40, EGP40, MK-1

Specifications for CD326 (EpCAM) Antibody, anti-mouse, REAfinity™

Overview

Clone REA977 recognizes the CD326 (EpCAM) antigen, which is a 40 kDa transmembrane glycoprotein involved in cell adhesion, cell proliferation, and tumor progression. It functions as a homotypic calcium-independent cell adhesion molecule. CD326 (EpCAM) is broadly expressed on epithelial cells including definitive endoderm cells, keratinocytes, immature thymocytes, langerhans cells, lymph node dendritic cells, thymic dendritic cells, splenic dendritic cells, and tumor cells including almost all carcinomas. Moreover, CD326 (EpCAM) is expressed on mouse embryonic stem cells and was described as a marker for the identification of successfully reprogrammed induced pluripotent stem cells (iPS).
Additional information: Clone REA977 displays negligible binding to Fc receptors.

Alternative names

Ep-CAM, EGP, KSA, TROP1, Ly74, Tacsd1, Tacstd1, GP40, EGP40, MK-1

Detailed product information

Technical specifications

CloneREA977
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD326 (EpCAM)
Alternative names of antigenEp-CAM, EGP, KSA, TROP1, Ly74, Tacsd1, Tacstd1, GP40, EGP40, MK-1
Molecular mass of antigen [kDa]33
Distribution of antigenstem cells, dendritic cells, epithelial cells, keratinocytes, Langerhans cells, tumor cells, cancer stem cells, ES and iPS cells, lung
Entrez Gene ID17075
RRIDAB_2728028, AB_2728052, AB_2728029, AB_2728053, AB_2728030, AB_2728058, AB_2728033, AB_2728059, AB_2728060, AB_2728034, AB_2728054, AB_2728031, AB_2728055, AB_2728056, AB_2728057, AB_2728032, AB_2728050, AB_2728027, AB_2728051

Resources for CD326 (EpCAM) Antibody, anti-mouse, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD326 (EpCAM) Antibody, anti-mouse, REAfinity™

Publications

  1. Borkowski, T. A. et al. (1996) Expression of gp40, the murine homologue of human epithelial cell adhesion molecule (Ep-CAM), by murine dendritic cells. Eur. J. Immunol. 26(1): 110-114
  2. Nelson, A. J. et al. (1996) The murine homolog of human Ep-CAM, a homotypic adhesion molecule, is expressed by thymocytes and thymic epithelial cells. Eur. J. Immunol. 26(2): 401-408
  3. Chen, H. F. et al. (2011) Surface marker epithelial cell adhesion molecule and E-cadherin facilitate the Stem Cell Rev. 7(3): 722-735

Related products for
CD326 (EpCAM) Antibody, anti-mouse, REAfinity™

3 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?