Clone:
REA1068
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC
Alternative names:
FCER1G, FcR-gamma, Fce1g, FcepsilonRI, Ly-50, FcεRII

Specifications for CD23 Antibody, anti-mouse, REAfinity™

Overview

Clone REA1068 recognizes mouse CD23, also known as low affinity IgE Fc receptor (FcεRII), a type II integral membrane glycoprotein. CD23 is expressed on activated B cells, follicular dendritic cells of immunized mice, on a subset of splenic dendritic cells, and mature B cells, but not on CD5
+
B-1 cells.
Additional information: Clone REA1068 displays negligible binding to Fc receptors.

Alternative names

FCER1G, FcR-gamma, Fce1g, FcepsilonRI, Ly-50, FcεRII

Detailed product information

Technical specifications

CloneREA1068
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD23
Alternative names of antigenFCER1G, FcR-gamma, Fce1g, FcepsilonRI, Ly-50, FcεRII
Molecular mass of antigen [kDa]8
Distribution of antigenB cells, dendritic cells, mature B cells, B cell subsets
Entrez Gene ID14127
RRIDAB_2733788, AB_2733359, AB_2733218, AB_2734014

References for CD23 Antibody, anti-mouse, REAfinity™

Publications

  1. Rao, M. et al. (1987) Characterization of a monoclonal antibody directed against the murine B lymphocyte receptor for IgE. J. Immunol. 138: 1845-1851
  2. Maeda, K. et al. (1992) Murine follicular dendritic cells and low affinity Fc receptors for IgE (Fc epsilon RII). J. Immunol. 148: 2340 -2347
  3. Cho, S. W. et al. (1997)
    B cell activation and Ig, especially IgE, production is inhibited by high CD23 levels
    in vivo
    and
    in vitro
    J. Immunol. 180(1): 36-46

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