Clone:
caa8-28H10
Type of antibody:
Primary antibodies
Isotype:
rat IgG2a
Applications:
FC
Alternative names:
Langerin

Specifications for CD207 (Langerin) Antibody, anti-mouse

Overview

CD207, also known as Langerin is a 48kDa transmembrane type II C-type lectin containing a single carbohydrate recognition domain in its extracellular region. Langerin is specifically expressed on epidermal Langerhans cells and dermal CD103
+
dendritic cells. It displays Ca
2+
-dependent binding specificity for mannose, N-acetyl-glucosamine, and fucose and is involved in antigen recognition, uptake and transport to the Birbeck granules, whose formation is dependent on Langerin expression. The CD207 epitope shows trypsin as well as collagenase sensitivity.

Alternative names

Langerin

Detailed product information

Technical specifications

Clonecaa8-28H10
Clonalitymonoclonal
Isotyperat IgG2a
Isotype controlIsotype Control Antibody, rat IgG2a
Hostrat
Type of antibodyPrimary antibodies
Speciesmouse
AntigenCD207 (Langerin)
Alternative names of antigenLangerin
Molecular mass of antigen [kDa]38
Distribution of antigendendritic cells, Langerhans cells
Entrez Gene ID246278
RRIDAB_2656237, AB_2656238, AB_2656239, AB_2656240, AB_2656241, AB_2656236

Resources for CD207 (Langerin) Antibody, anti-mouse

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

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