Type of antibody:
Primary antibodies, Recombinant antibodies
recombinant human IgG1
Alternative names:
CXCR1, C-C, C-C-CKR-1, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA

Specifications for CD181 (CXCR1) Antibody, anti-human, REAfinity™


Clone REA958 recognizes the human CD181 antigen, a multi-pass membrane protein also known as C-X-C chemokine receptor type 1 (CXCR1) or IL-8 receptor A (IL-8RA). CD181 is expressed as homodimer or heterodimer with CD182 (CXCR2) and found on granulocytes, natural killer (NK) cells, a subset of T lymphocytes, mast cells, monocytes, endothelial cells, megakarocytes, and oligodendrocytes. It is one of two high-affinity receptors for interleukin 8 (IL-8), a major mediator of immune and inflammatory responses implicated in many disorders, including tumor growth. IL-8, released in response to inflammatory stimuli, binds to the extracellular part of CD181. The ligand-activated intracellular signaling pathways results in neutrophil migration to the site of inflammation.
Additional information: Clone REA958 displays negligible binding to Fc receptors.

Alternative names

CXCR1, C-C, C-C-CKR-1, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA

Detailed product information

Technical specifications

Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
AntigenCD181 (CXCR1)
Alternative names of antigenCXCR1, C-C, C-C-CKR-1, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA
Molecular mass of antigen [kDa]40
Distribution of antigenendothelial cells, granulocytes, lymphocytes, mast cells, megakaryocytes, monocytes, NK cells, oligodendrocytes
Entrez Gene ID3577
RRIDAB_2727233, AB_2727277, AB_2727234, AB_2727278, AB_2727235, AB_2727282, AB_2727240, AB_2727281, AB_2727239, AB_2727283, AB_2727241, AB_2727279, AB_2727236, AB_2727237, AB_2727280, AB_2727238, AB_2801895, AB_2727276

Resources for CD181 (CXCR1) Antibody, anti-human, REAfinity™


Please follow this
to search for Certificates of Analysis (CoA) by lot number.

References for CD181 (CXCR1) Antibody, anti-human, REAfinity™


  1. Holmes, W. E. et al. (1991) Structure and functional expression of a human interleukin-8 receptor. Science 253(5025): 1278
  2. Cummings, C. J. et al. (1999) Expression and function of the chemokine receptors CXCR1 and CXCR2 in sepsis. J. Immunol. 162(4): 2341-2346

Related products for
CD181 (CXCR1) Antibody, anti-human, REAfinity™

1 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?