Clone:
REA955
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MC
Alternative names:
KIR2DL5A, KIR2DL5B

Extended validation for CD158f (KIR2DL5) Antibody, anti-human, REAfinity™

Sensitivity

Fixation data
To provide an indication on how an antibody performs after fixation of cells, in-house data on staining results before and after fixation with 3.7% formaldehyde using Miltenyi Biotec antibodies are provided. Different experimental settings may lead to different results.
No fixation
Post fixation
View details
Comparison of staining pattern on non-fixed and fixed cells using CD158f (KIR2DL5) (REA955). The performance of the antibody after fixation was tested by comparing the staining pattern on fresh (no fixation) versus fixed (post fixation) cells.
View details
Comparison of staining pattern on non-fixed and fixed cells using CD158f (KIR2DL5) (REA955). The performance of the antibody after fixation was tested by comparing the staining pattern on fresh (no fixation) versus fixed (post fixation) cells.
Comparison of staining pattern on non-fixed and fixed cells using CD158f (KIR2DL5) (REA955). The performance of the antibody after fixation was tested by comparing the staining pattern on fresh (no fixation) versus fixed (post fixation) cells.

Specifications for CD158f (KIR2DL5) Antibody, anti-human, REAfinity™

Overview

Clone REA955 recognizes the human CD158f (KIR2DL5) antigen, a member of the killer immunoglobulin-like receptor (KIR) family, which recognizes subsets of HLA alleles. Expression is found mainly on CD56
dim
CD16
+
natural killer (NK) cells but also on a subset of CD8
+
T cells. KIRs are monomeric receptors possessing high allelic polymorphism, with either two or three Ig-like extracellular domains.
Additional information: Clone REA955 displays negligible binding to Fc receptors.

Alternative names

KIR2DL5A, KIR2DL5B

Detailed product information

Technical specifications

CloneREA955
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD158f (KIR2DL5)
Alternative names of antigenKIR2DL5A, KIR2DL5B
Molecular mass of antigen [kDa]38
Distribution of antigenNK cells, T cells, CD8+ T cells
Entrez Gene ID57292
RRIDAB_2727257, AB_2727215, AB_2727258, AB_2727216, AB_2727260, AB_2727218, AB_2727259, AB_2727217, AB_2727256, AB_2727214

Resources for CD158f (KIR2DL5) Antibody, anti-human, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD158f (KIR2DL5) Antibody, anti-human, REAfinity™

Publications

  1. Gomez-Lozano, N. et al. (2002) Some human KIR haplotypes contain two KIR2DL5 genes: KIR2DL5A and KIR2DL5B. Immunogenetics 54(5): 314-319
  2. Estefania, E. et al. (2007) Human KIR2DL5 is an inhibitory receptor expressed on the surface of NK and T lymphocyte subsets. J. Immunol. 178(7): 4402-4410
  3. Gomez-Lozano, N. et al. (2007) Epigenetic silencing of potentially functional KIR2DL5 alleles: Implications for the acquisition of KIR repertoires by NK cells. Eur. J. Immunol. 37(7): 1954-1965

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