Clone:
97C5
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ, mouse IgG1
Applications:
FC, MICS, IF, IHC, MC
Alternative names:
MME, CALLA, NEP, SFE, gp100

Specifications for CD10 Antibody, anti-human

Overview

Clone 97C5 recognizes the human CD10 antigen, the human common acute lymphoblastic leukemia antigen (CALLA). CD10 is a 100 kDa cell surface molecule identical to human membrane-associated neutral endopeptidase (NEP) and also known as neprilysin or enkephalinase. Human CD10 is expressed on a wide variety of normal and neoplastic cell types from different tissues including neural and hematopoietic cells. It is expressed on pre– and pro–B cells and is involved in B cell development and differentiation. The antigen is also present on mature neutrophils, T cell precursors, and some T cell leukemias/lymphomas. Furthermore, CD10 is expressed on neoplastic cells of several B lymphoid leukemias/lymphomas.

Alternative names

MME, CALLA, NEP, SFE, gp100

Detailed product information

Technical specifications

Clone97C5
Clonalitymonoclonal
Isotypemouse IgG1κ, mouse IgG1
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD10
Alternative names of antigenMME, CALLA, NEP, SFE, gp100
Molecular mass of antigen [kDa]85
Distribution of antigenB cells, epithelial cells, fibroblasts, granulocytes, ILC, stromal cells, T cells, leukemia cells, ES and iPS cells, bone marrow, brain, smooth muscle, gut, kidney
Entrez Gene ID4311
RRIDAB_2733329, AB_2857649, AB_2857621, AB_2819598, AB_2819583, AB_2660864, AB_2660858, AB_2660859, AB_2660860, AB_2660861, AB_2660862, AB_2660863, AB_10831358, AB_2904674, AB_2904673, AB_2733328

Resources for CD10 Antibody, anti-human

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD10 Antibody, anti-human

Publications

  1. Shipp, M. A. and Look, A. T. (1993) Hematopoietic differentiation antigens that are membrane-associated enzymes: cutting is the key! Blood 82: 1052-1070
  2. Kalled, S. L. et al. (1995) The distribution of CD10 (NEP 24.11, CALLA) in human and mice is similar in non-lymphoid organs but differ within the hematopoietic system: absence on murine T and B lymphoid progenitors. Eur. J. Immunol. 25: 677-687

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