Clone:
REAL807
Type of antibody:
Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Applications:
MICS, IHC, IF
Alternative names:
Ksp-cadherin, Kidney-specific cadherin, CDH16

Specifications for Cadherin-16 Antibody, anti-human, REAdye_lease™

Overview

Clone REAL807 is an antibody fragment derived from the full Cadherin-16 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL807 recognizes the human Cadherin-16 glycoprotein, also known as Ksp-cadherin, encoded by the CDH16 gene. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Expression is exclusively in the kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Alternative names

Ksp-cadherin, Kidney-specific cadherin, CDH16

Detailed product information

Technical specifications

CloneREAL807
Clonalitymonoclonal
Isotype controlControl Antibody
Hosthuman cell line
Type of antibodyReleasable fluorochromes, Primary antibodies, Recombinant antibodies
Specieshuman
AntigenCadherin-16
Alternative names of antigenKsp-cadherin, Kidney-specific cadherin, CDH16
Distribution of antigenkidney

Resources for Cadherin-16 Antibody, anti-human, REAdye_lease™

Certificates

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References for Cadherin-16 Antibody, anti-human, REAdye_lease™

Publications

  1. Wendeler, M. W. et al. (2004) Ksp-cadherin is a functional cell-cell adhesion molecule related to LI-cadherin. Exp. Cell Res. 294(2): 345-355
  2. Thedieck, C. et al. (2005) Expression of Ksp-cadherin during kidney development and in renal cell carcinoma. Br. J. Cancer 92(11): 2010-2017
  3. Calì, G. et al. (2012) CDH16/Ksp-cadherin is expressed in the developing thyroid gland and is strongly down-regulated in thyroid carcinomas. Endocrinology 153(1): 522-534

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