CD45RC antibodies, rat

CD45RC antibodies, rat

Clone: REA1000 | Dilution: 1:50
Clone REA1000 recognizes the RC isoform of the rat CD45 antigen, also known as leukocyte common antigen (LCA), which is a single-chain type I transmembrane glycoprotein. CD45 has multiple isoforms and differential glycosylation, CD45RC is the high molecular weight form of CD45. CD45 is expressed at high levels on all cells of hematopoietic origin except for erythrocyte and platelets. It plays a role in signal transduction through B and T cell antigen receptors. The CD45RC isoform is expressed on B cells, most cytotoxic T cells, and a subset of T helper cells, but not expressed on myeloid cells.
Additional information: Clone REA1000 displays negligible binding to Fc receptors.

Alternative names

CD45, LCA, L-CA

Technical specifications

  • Antigen: CD45RC
  • Clone: REA1000
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: CD45, LCA, L-CA
  • Entrez Gene ID: 24699
  • Molecular mass of antigen [kDa]: 141
  • Distribution of antigen: B cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, VioBlue, PE-Vio615, PE-Vio770, APC-Vio770, VioBright 515, Biotin, FITC
  • Selected references

    1. Sunderland, C. A. et al. (1979) Purification with monoclonal antibody of a predominant leukocyte-common antigen and glycoprotein from rat thymocytes. Eur. J. Immunol. 9(2): 155-159
    2. Mojcik, D. L. et al. (1987) Monoclonal antibodies to RT7 and LCA antigens in the rat: cell distribution and segregation analysis. Hybridoma 6(5): 531-543
Product options: 13
130-116-898

CD45RC-FITC, rat

30 µg in 200 µL (1)
AUD 52.00
130-116-899

CD45RC-PE, rat

30 µg in 200 µL (1)
AUD 67.00
130-116-779

CD45RC-PE, rat

150 µg in 1 mL (1)
AUD 255.00
130-116-900

CD45RC-APC, rat

30 µg in 200 µL (1)
AUD 96.00
130-116-780

CD45RC-APC, rat

150 µg in 1 mL (1)
AUD 293.00
30 µg in 200 µL (1)
AUD 140.00
30 µg in 200 µL (1)
AUD 118.00
150 µg in 1 mL (1)
AUD 337.00
30 µg in 200 µL (1)
AUD 118.00
30 µg in 200 µL (1)
AUD 126.00
30 µg in 200 µL (1)
AUD 125.00
150 µg in 1 mL (1)
AUD 449.00
30 µg in 200 µL (1)
AUD 37.00

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