CD45RA antibodies, human

CD45RA antibodies, human

Clone: REA562 | Dilution: 1:50
Clone REA562 recognizes the human CD45RA antigen, which is expressed on naive CD4
+
and CD8
+
T cells as well as on CD8
+
effector T cells. CD45RA is also present on subsets of B and NK cells as well as on plasmacytoid dendritic cells. The CD45RA antibody recognizes the 220 kDa isoform of the leukocyte common antigen (LCA), a transmembrane tyrosine phosphatase.
Additional information: Clone REA562 displays negligible binding to Fc receptors

Alternative names

Ptprc, B220, CD45R, GP180, L-CA, LY5, T200

Technical specifications

  • Antigen: CD45RA
  • Clone: REA562
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: Ptprc, B220, CD45R, GP180, L-CA, LY5, T200
  • Entrez Gene ID: 5788
  • Molecular mass of antigen [kDa]: 145
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: T cells, B cells, NK cells, dendritic cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioGreen, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Braun, T. et al. (2012)
      Effector CD4
      +
      CD45RA
      CD25
      bright
      Foxp3
      bright
      regulatory T cell (eTreg) distribution is significantly impaired in chronic myelomonocytic leukemia (CMML) and correlates with TET 2 mutational status.
      Blood 120: 2808-2808
    2. Baba, N. et al. (2010)
      Interplay between CD45RA
      +
      regulatory T cells and TNF-α in the regulation of human Tʜ17 differentiation.
      Int. Immunol. 22: 237-244
    3. Cantisan, S. et al. (2010)
      CD45RA expression on HCMV-specific effector memory CD8
      +
      T cells is associated with the duration and intensity of HCMV replication after transplantation.
      Clin. Immunol. 137(1): 81-88
Product options: 18
for 30
tests
(1)
AUD 92.00
for 100
tests
(1)
AUD 271.00
130-113-928

CD45RA-PE, human

for 30
tests
(1)
AUD 123.00
130-113-366

CD45RA-PE, human

for 100
tests
(1)
AUD 329.00
for 30
tests
(1)
AUD 157.00
for 100
tests
(1)
AUD 347.00
for 30
tests
(1)
AUD 157.00
for 100
tests
(1)
AUD 347.00
for 30
tests
(1)
AUD 157.00
for 100
tests
(1)
AUD 347.00
for 30
tests
(1)
AUD 161.00
for 100
tests
(1)
AUD 357.00
for 30
tests
(1)
AUD 142.00
for 100
tests
(1)
AUD 343.00
for 30
tests
(1)
AUD 138.00
for 100
tests
(1)
AUD 334.00
for 30
tests
(1)
AUD 92.00
for 100
tests
(1)
AUD 271.00

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