CD3ε (intracellular) antibodies, human and mouse

CD3ε (intracellular) antibodies, human and mouse

Clone: REA975 | Dilution: 1:50
Clone REA975 recognizes an intracellular part of the CD3ε chain (activation epitope). CD3ε is a single-pass type I membrane protein, which is a part of the CD3 complex and a subunit of the TCR complex. The CD3 complex mediates signal transduction in several intracellular pathways and has a role in T cell activation and antigen recognition by binding the peptide/MHC antigen complex. CD3ε is expressed on all mature T lymphocytes, NKT cells, and during the development of thymocytes.
Additional information: Clone REA975 displays negligible binding to Fc receptors.

Alternative names

CD3e, CD3epsilon, T3E

Technical specifications

  • Antigen: CD3ε (intracellular)
  • Clone: REA975
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: CD3e, CD3epsilon, T3E
  • Entrez Gene ID: 916
  • Molecular mass of antigen [kDa]: 21
  • Distribution of antigen: T cells, NKT cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, Vio515, Vio667
  • Selected references

    1. Gold, D. P. et al. (1987) Evolutionary relationship between the T3 chains of the T-cell receptor complex and the immunoglobulin supergene family. Proc. Natl. Acad. Sci. U.S.A. 84(21): 7649-7653
    2. Clevers, H. et al. (1988) Characterization and expression of the murine CD3-epsilon gene. Proc. Natl. Acad. Sci. U.S.A. 85(22): 8623-8627
    3. Soudais, C. et al. (1993) Independent mutations of the human CD3-epsilon gene resulting in a T cell receptor/CD3 complex immunodeficiency. Nat. Genet. 3(1): 77-81
Product options: 10
for 30
tests
(1)
AUD 95.00
for 100
tests
(1)
AUD 288.00
for 30
tests
(1)
AUD 124.00
for 100
tests
(1)
AUD 340.00
for 30
tests
(1)
AUD 161.00
for 100
tests
(1)
AUD 358.00
for 30
tests
(1)
AUD 221.00
for 100
tests
(1)
AUD 344.00
for 30
tests
(1)
AUD 161.00
for 100
tests
(1)
AUD 358.00

Related products

3 products available