CD253 antibodies, mouse

CD253 antibodies, mouse

Clone: N2B2 | Dilution: 1:10
Clone N2B2 reacts with murine CD253, a type 2 transmembrane protein, also known as TNF-related apoptosis-inducing ligand (TRAIL), APO-2 ligand (APO-2L), or TNF ligand superfamily member 10 (TNFSF10). CD253 is expressed on a variety of cells of the innate and adaptive immune system, including natural killer (NK) cells. Often expression is induced or upregulated upon activation. CD253 can trigger apoptosis through trimerization of death receptor DR5 (TRAILR). The N2B2 antibody is reported to block CD253-mediated NK cell cytotoxicity
in vitro
.

Alternative names

TNFSF10, APO2L, Ly81, TL2, TRAIL

Technical specifications

  • Antigen: CD253
  • Clone: N2B2
  • Isotype: rat IgG2aκ
  • Isotype control: Rat IgG2a – isotype control antibodies
  • Alternative names of antigen: TNFSF10, APO2L, Ly81, TL2, TRAIL
  • Entrez Gene ID: 22035
  • Molecular mass of antigen [kDa]: 33
  • Distribution of antigen: B cells, dendritic cells, gut, kidney, lung, monocytes, NK cells, spleen, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, VioBlue, Biotin, FITC
Product options: 5
30 µg in 1 mL (1)
AUD 54.00
130-102-562

CD253-PE, mouse

30 µg in 1 mL (1)
AUD 70.00
130-102-510

CD253-APC, mouse

30 µg in 1 mL (1)
AUD 103.00
30 µg in 1 mL (1)
AUD 146.00
30 µg in 1 mL (1)
AUD 39.00

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