CD21/CD35 antibodies, mouse

CD21/CD35 antibodies, mouse

Clone: REA800 | Dilution: 1:50
Clone REA800 recognizes an epitope shared by mouse CD21 and CD35, also known as CR2 and CR1. CD21 and CD35 are alternatively spliced transcripts from the Cr2 gene, which produce cell-surface proteins of 145 and 190 kDa, respectively. CD21 and CD35 are expressed on the majority of peripheral B lymphocytes, on the majority of resident peritoneal macrophages, on mast cells, activated granulocytes, and follicular dendritic cells. CD21 forms part of a signal transduction complex with CD19 and CD81, which are associated with the antigen receptor on B lymphocytes.
Additional information: Clone REA800 displays negligible binding to Fc receptors.

Alternative names

CR2, C3dR, C3b/C4b-R, CR1, EBV-R, Immune adherence receptor

Technical specifications

  • Antigen: CD21/CD35
  • Clone: REA800
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: CR2, C3dR, C3b/C4b-R, CR1, EBV-R, Immune adherence receptor
  • Entrez Gene ID: 12902
  • Molecular mass of antigen [kDa]: 112
  • Distribution of antigen: B cells, basophils, dendritic cells, eosinophils, granulocytes, lymphocytes, macrophages, monocytes, neutrophils, NK cells, platelets, red blood cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, Biotin
  • Selected references

    1. Kozono, Y. et al. (1998) Cross-linking CD21/CD35 or CD19 increases both B7-1 and B7-2 expression on murine splenic B cells. J. Immunol. 160(4): 1565-1572
    2. Brockman, M. A. et al. (2006) Optimal long-term humoral responses to replication-defective herpes simplex virus require CD21/CD35 complement receptor expression on stromal cells. J. Virol. 80(14): 7111-7117
    3. Roozendaal, R. et al. (2007) Complement receptors CD21 and CD35 in humoral immunity. Immunol. Rev. 219: 157-166
Product options: 18
30 µg in 200 µL (1)
AUD 54.00
150 µg in 1 mL (1)
AUD 233.00
30 µg in 200 µL (1)
AUD 70.00
150 µg in 1 mL (1)
AUD 268.00
30 µg in 200 µL (1)
AUD 101.00
150 µg in 1 mL (1)
AUD 307.00
30 µg in 200 µL (1)
AUD 148.00
150 µg in 1 mL (1)
AUD 354.00
30 µg in 200 µL (1)
AUD 124.00
150 µg in 1 mL (1)
AUD 325.00
30 µg in 200 µL (1)
AUD 132.00
150 µg in 1 mL (1)
AUD 344.00
30 µg in 200 µL (1)
AUD 117.00
150 µg in 1 mL (1)
AUD 354.00
30 µg in 200 µL (1)
AUD 130.00
150 µg in 1 mL (1)
AUD 472.00
30 µg in 200 µL (1)
AUD 39.00
150 µg in 1 mL (1)
AUD 173.00

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