CD158i (KIR2DS4) antibodies, human

CD158i (KIR2DS4) antibodies, human

Clone: JJC11.6 | Dilution: 1:11
Clone JJC11.6 recognizes CD158i (KIR2DS4), a member of the killer immunoglobulin-like receptor (KIR) family expressed on natural killer (NK) cells. CD158i (KIR2DS4) provides an activation signal for NK lytic activity upon interaction with its ligand, HLA-Cw4, in an antigen-independent manner.
KIRs are monomeric receptors possessing high allelic polymorphism with either 2 or 3 Ig-like extracellular domains. The receptor family can be subdivided functionally according to the length of their cytoplasmic tail in inhibitory and activating KIRs.

Alternative names

KIR2DS4

Technical specifications

  • Antigen: CD158i (KIR2DS4)
  • Clone: JJC11.6
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: KIR2DS4
  • Entrez Gene ID: 3809
  • Molecular mass of antigen [kDa]: 31
  • Distribution of antigen: NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, Biotin, pure
  • Selected references

    1. Kratz, G. et al. (2004) MHC Class I-independent recognition of NK-activating receptor KIR2DS4. J. Immunol. 173: 1819-1825
    2. Djeu, J. et al. (2002) A view to a kill: signals triggering cytotoxicity. Clin. Cancer Res. 8: 636-640
    3. Hsu, K. et al. (2002) The killer cell immunoglobin-like (KIR) genomic region: gene-order, haplotypes and allelic polymorphism. Immunol. Rev. 190: 40-52
    4. Selvakumar, A. et al. (1997) Polymorphism and domain variability of human killer cell inhibitory receptors. Immunol. Rev. 155: 183-196
Product options: 8
for 30
tests
(1)
AUD 124.00
for 100
tests
(1)
AUD 336.00
for 30
tests
(1)
AUD 163.00
for 100
tests
(1)
AUD 363.00
for 30
tests
(1)
AUD 163.00
for 100
tests
(1)
AUD 363.00
for 100
tests
(1)
AUD 280.00
100 µg in 1 mL
AUD 157.00

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