CD107a (LAMP-1) antibodies, human

CD107a (LAMP-1) antibodies, human

Clone: REA792 | Dilution: 1:50
Clone REA792 recognizes the CD107a antigen, also known as lysosome-associated membrane protein 1 (LAMP-1), a 110–140 kDa type I membrane glycoprotein. It is a widely expressed intracellular protein, located in the lysosomal/endosomal membrane. CD107a transiently located on the plasma membrane can be used as a marker for CD8
+
T cell degranulation following stimulation. It is also expressed to a lower extent on activated NK cells.
Additional information: Clone REA792 displays negligible binding to Fc receptors.

Alternative names

LAMP-1, LAMPA, LGP120, LAMP1

Technical specifications

  • Antigen: CD107a (LAMP-1)
  • Clone: REA792
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: LAMP-1, LAMPA, LGP120, LAMP1
  • Entrez Gene ID: 3916
  • Molecular mass of antigen [kDa]: 42
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    pigtail monkey (
    Macaca nemestrina
    )
    ,
    african green monkey (
    Chlorocebus aethiops
    )
    , baboon,
    chimpanzee (
    Pan troglodytes
    )
  • Distribution of antigen: dendritic cells, endothelial cells, epithelial cells, granulocytes, macrophages, neutrophils, platelets, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, Vio667, Biotin
  • Selected references

    1. Fukuda, M. et al. (1988) Cloning of cDNAs encoding human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Comparison of their deduced amino acid sequences. J. Biol. Chem. 263(35): 18920-18928
    2. Mane, S. M. et al. (1989) Purification and characterization of human lysosomal membrane glycoproteins. Arch Biochem Biophys. 268(1): 360-378
    3. Betts, M. R. et al. (2003)
      Sensitive and viable identification of antigen-specific CD8
      +
      T cells by a flow cytometric assay for degranulation.
      J. Immunol. Methods 281: 65-78
Product options: 24
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AUD 334.00
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AUD 165.00
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AUD 365.00
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AUD 126.00
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AUD 334.00
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AUD 165.00
for 100
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AUD 365.00
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(1)
AUD 165.00
for 100
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AUD 365.00
for 30
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(1)
AUD 165.00
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AUD 365.00
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AUD 146.00
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AUD 348.00
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tests
(1)
AUD 146.00
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AUD 348.00
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AUD 227.00
for 100
tests
(1)
AUD 453.00
for 30
tests
(1)
AUD 165.00
for 100
tests
(1)
AUD 365.00
for 30
tests
(1)
AUD 97.00
for 100
tests
(1)
AUD 284.00

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