Anti-iNKT antibodies, human

Anti-iNKT antibodies, human

Clone: 6B11 | Dilution: 1:11
NKT cells represent a distinct lymphocyte population that co-expresses T cell and NK cell surface markers. A subset of human NKT cells, referred to as iNKT cells, expresses an invariant TCR α-chain with certain TCR β-chains (Vα24-Jα18 combined with Vβ11). The iNKT cells are implicated in immunoregulatory processes such as tolerance, host defense, and tumor surveillance.

Technical specifications

  • Antigen: iNKT
  • Clone: 6B11
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Entrez Gene ID: 28659, 28747, 28582, 28581
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: NKT cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, Biotin
  • Selected references

    1. Exley, M. et al. (2008) Selective activation, expansion, and monitoring of human iNKT cells with a monoclonal antibody specific for the TCR α-chain CDR3 loop. Eur. J. Immunol. 38: 1756-1766
    2. Montoya, J. C. et al. (2007) Characterization of human invariant natural killer T subsets in health and disease using a novel invariant natural killer T cell-clonotypic monoclonal antibody, 6B11. Immunology 122: 1-14
Product options: 8
for 30
tests
(1)
AUD 124.00
for 100
tests
(1)
AUD 336.00
for 30
tests
(1)
AUD 163.00
for 100
tests
(1)
AUD 363.00
for 30
tests
(1)
AUD 163.00
for 100
tests
(1)
AUD 363.00
for 30
tests
(1)
AUD 97.00
for 100
tests
(1)
AUD 280.00

Related products

4 products available