Anti-IL-6 antibodies, human

Anti-IL-6 antibodies, human

Clone: REA1037
Clone REA1037 recognizes the Interleukin 6 (IL-6) antigen, which is originally identified as a B cell differentiation factor Il-6 is a multifunctional cytokine, which regulates immune responses, hematopoiesis, acute phase responses, and inflammatory reactions. It induces the terminal maturation of activated B cells into antibody-secreting plasma cells and acts in synergy with IL-3 to support the proliferation of hematopoietic stem cells. IL-6 is produced by many cell types, such as monocytes, fibroblasts, endothelial cells, eosinophils, and T cells. Disturbed IL-6 production has been associated with pathological processes, including inflammatory autoimmune diseases and cancer.
Additional information: Clone REA1037 displays negligible binding to Fc receptors.

Alternative names

BSF2, HGF, HSF, IFNB2

Technical specifications

  • Antigen: IL-6
  • Clone: REA1037
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: BSF2, HGF, HSF, IFNB2
  • Entrez Gene ID: 3569
  • Molecular mass of antigen [kDa]: 21
  • Distribution of antigen: monocytes, fibroblasts, endothelial cells, eosinophils, T cells
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
Product options: 1
100 µg in 100 µL
AUD 253.00