Anti-H-2Db antibodies, mouse

Anti-H-2D
b
antibodies
, mouse

Clone: REA619 | Dilution: 1:50
Clone REA619 recognizes the mouse H-2D
b
MHC class I alloantigen expressed on mouse MHC class I
+
cells of the H-2D
b
haplotype. Reactivity to other haplotypes like, for example, a, d, f, k, n, p, q, r, s, u, and v, has not been observed.
Additional information: Clone REA619 displays negligible binding to Fc receptors.

Alternative names

MHC class I, H-2D, H2-D

Technical specifications

  • Antigen:
    H-2D
    b
  • Clone: REA619
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: MHC class I, H-2D, H2-D
  • Entrez Gene ID: 14964
  • Distribution of antigen: ubiquitous
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC-Vio770
  • Selected references

    1. Glithero, A. et al. (1999) Crystal structures of two H-2Db/glycopeptide complexes suggest a molecular basis for CTL cross-reactivity. Immunity 10(1): 63-74
    2. Pascolo, S. et al. (1997)
      HLA-A2.1-restricted education and cytolytic activity of CD8
      +
      T lymphocytes from beta2 microglobulin (beta2m) HLA-A2.1 monochain transgenic H-2Db beta2m double knockout mice.
      J. Exp. Med. 185(12): 2043-2051
    3. van Stipdonk, M. J. et al. (2009) Design of agonistic altered peptides for the robust induction of CTL directed towards H-2Db in complex with the melanoma-associated epitope gp100. Cancer Res. 69(19): 7784-7792
Product options: 1
30 µg in 200 µL (1)
AUD 126.00

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