Anti-Carbonic Anhydrase 9 antibodies, human

Anti-Carbonic Anhydrase 9 antibodies, human

Clone: REA658 | Dilution: 1:11
Clone REA658 recognizes the human carbonic anhydrase IX, a single-pass type I integral membrane protein detected in HeLa cells and in different human carcinomas. This tumor-associated isoenzyme is also expressed on the surface microvilli and in the nucleus. Carbonic anhydrase IX, also known as CAIX, CA9, or MN, is a member of the alpha-carbonic anhydrase family that catalyze the reversible hydration of carbon dioxide. It may plays a role in the control of cell proliferation and transformation and seems to be a novel specific biomarker for identifying cervical dysplasia and carcinoma. Carbonic anhydrases participate in a variety of biological processes.
Additional information: Clone REA658 displays negligible binding to Fc receptors.

Alternative names

Carbonic anhydrase IX, CA9, CAIX, CA-IX, MN

Technical specifications

  • Antigen: Carbonic Anhydrase 9
  • Clone: REA658
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: Carbonic anhydrase IX, CA9, CAIX, CA-IX, MN
  • Entrez Gene ID: 768
  • Molecular mass of antigen [kDa]: 46
  • Distribution of antigen: cancer cells, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, Biotin
  • Selected references

    1. Pastorek, J. et al. (1994) Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment. Oncogene 9(10): 2877-2888
    2. Opavsky, R. et al. (1996) Human MN/CA9 gene, a novel member of the carbonic anhydrase family: structure and exon to protein domain relationships. Genomics 33(3): 480-487
Product options: 6
for 30
tests
(1)
AUD 126.00
for 100
tests
(1)
AUD 334.00
for 30
tests
(1)
AUD 165.00
for 100
tests
(1)
AUD 365.00
for 30
tests
(1)
AUD 97.00
for 100
tests
(1)
AUD 284.00

Related products

1 products available