UltraMicroscope II

Light sheet microscopy for 3D imaging and analysis of entire biological systems

Light sheet fluorescence microscopy with the UltraMicroscope II enables you to visualize whole biological systems. Moving the sample through the light sheets allows the generation of sharp and bright 3D images. Whether imaging large tissue samples or even entire organs, you are equipped for the task at hand regardless of the clearing protocol and imaging solution being used.

Benefits

User friendly

An intuitive design, short training time for new users, and minimal staff support requirements make this light sheet microscope the perfect tool for imaging facilities.

Easy adaptation

Apply any clearing protocol and make use of the automated refractive index compensation to maintain high image quality. 

High flexibility

Benefit from our objective lens series designed and optimized specifically for light sheet imaging. Our modular light sheet technology can be tailored to your needs.

From overview to cellular imaging

Explore cellular details in high resolution without losing sight of the big picture.

Features and specifications

The UltraMicroscope II comes in two configurations

Both setups feature an easy-to-access sample chamber, which can accommodate large samples. Homogeneous fluorescence excitation is achieved by six light sheets that illuminate the sample from both sides. 

The Super Plan configuration includes an automated detection unit delivering unprecedented image resolution and quality. Specially developed for light sheet microscopy, the MI Plan objective series maximizes the imaging performance in all clearing media. The Super Plan Module is also available as an upgrade for existing UltraMicroscope II systems. With its easy handling and magnification adjustment, the Zoom body configuration is the ideal choice for a multi-user environment.

Super Plan configuration

UMII Super

Optimal sensitivity

Latest sCMOS cameras with large field of view and excellent sensitivity guarantee outstanding data quality.

Automated detection unit

The automated magnification changer (0.6×, 1×, 1.66×, and 2.5×) and chromatic correction enable high-resolution multicolor imaging.

MI Plan objective lenses

Optimized and developed for high-resolution light sheet microscopy – even for large samples. Compatible with all clearing media.

Large sample chamber

The chamber can host entire rodent organs, rodent tumors, and mouse embryos.

1 2 3 4

Optimal sensitivity

Latest sCMOS cameras with large field of view and excellent sensitivity guarantee outstanding data quality.

Automated detection unit

The automated magnification changer (0.6×, 1×, 1.66×, and 2.5×) and chromatic correction enable high-resolution multicolor imaging.

MI Plan objective lenses

Optimized and developed for high-resolution light sheet microscopy – even for large samples. Compatible with all clearing media.

Large sample chamber

The chamber can host entire rodent organs, rodent tumors, and mouse embryos.

UMII Super

Zoom body configuration

UMII Zoom

Optimal sensitivity

Latest sCMOS cameras with large field of view and excellent sensitivity guarantee outstanding data quality.

Motorized tube lens

Chromatic correction enables acquisition of perfectly aligned multicolor images.

Easy zooming

The zoom body configuration is ideal for multi-user environ­ments. Magnification is adjusted by simply turning the zoom dial.

Large sample chamber

The chamber can host entire rodent organs, rodent tumors, and mouse embryos.

1 2 3 4

Optimal sensitivity

Latest sCMOS cameras with large field of view and excellent sensitivity guarantee outstanding data quality.

Motorized tube lens

Chromatic correction enables acquisition of perfectly aligned multicolor images.

Easy zooming

The zoom body configuration is ideal for multi-user environ­ments. Magnification is adjusted by simply turning the zoom dial.

Large sample chamber

The chamber can host entire rodent organs, rodent tumors, and mouse embryos.

UMII Zoom
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UltraMicroscope II

3D imaging and analysis of entire biological systems

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