Clone:
REAL872
Type of antibody:
Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Applications:
MICS, IHC, IF
Alternative names:
Synapsin 1, Synapsin I, Syn1, SYN-1

Specifications for Synapsin-1 Antibody, anti-human/mouse, REAdye_lease™

Overview

Clone REAL872 is an antibody fragment derived from the full Synapsin-1 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL872 recognizes the human and mouse neuron- specific phoshoprotein Synapsin-1. Synapsins are substrates for different protein kinases and involved in the regulation of neurotransmitter release. Synapsin-1 occurs in two isoforms (Synapsin Ia and Synapsin Ib) and belongs to the most specific markers of synapses throughout the central and peripheral nervous system.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Alternative names

Synapsin 1, Synapsin I, Syn1, SYN-1

Detailed product information

Technical specifications

CloneREAL872
Clonalitymonoclonal
Isotype controlControl Antibody
Hosthuman cell line
Type of antibodyReleasable fluorochromes, Primary antibodies, Recombinant antibodies
Specieshuman, mouse
Cross-reactivityrat
AntigenSynapsin-1
Alternative names of antigenSynapsin 1, Synapsin I, Syn1, SYN-1
Distribution of antigenneurons

Resources for Synapsin-1 Antibody, anti-human/mouse, REAdye_lease™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for Synapsin-1 Antibody, anti-human/mouse, REAdye_lease™

Publications

  1. Huttner, W. B. et al. (1983) Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation. J. Cell Biol. 96(5): 1374-1388
  2. Südhof, T. C. et al. (1989) Synapsins: mosaics of shared and individual domains in a family of synaptic vesicle phosphoproteins. Science 245(4925): 1474-1480
  3. Patzke, C. et al. (2019) Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses. Cell 179(2): 498-513

Related products for
Synapsin-1 Antibody, anti-human/mouse, REAdye_lease™

1 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?