REAlease® CD31 Complexes, mouse

REAlease
®
CD31 Complexes
, mouse

Clone: REAL260 | Dilution: 1:50
Clone REAL260 is an antibody fragment derived from the full CD31 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity.
Clone REAL260 recognizes the cell surface protein CD31. The murine CD31 antigen is also known as PECAM-1. The encoded protein is a single-pass type I membrane protein containing six Ig-like C2-type (immunoglobulin-like) domains and functions as cell adhesion molecule. CD31 is present on mature endothelial cells as well as on most leukocyte subtypes and platelets where the expression level can vary. Besides its function in exhibiting adhesive properties, the protein is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions.
The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.

Alternative names

PECAM1, Pecam, EndoCAM, GPIIa

Technical specifications

  • Antigen: CD31
  • Clone: REAL260
  • Isotype control: REAL Control
  • Alternative names of antigen: PECAM1, Pecam, EndoCAM, GPIIa
  • Distribution of antigen: endothelial cells, leukocytes, platelets
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC, PE
  • Selected references

    1. Xie, Y. and Muller, W. A. (1993) Molecular cloning and adhesive properties of murine platelet/endothelial cell adhesion molecule 1. Proc. Natl. Acad. Sci. U.S.A. 90(12): 5569-5573
    2. Woodfin, A. et al. (2007) PECAM-1: a multi-functional molecule in inflammation and vascular biology. Arterioscler. Thromb. Vasc. Biol. 27(12): 2514-2523
    3. van Buul, J. D. and Hordijk, P. L. (2008) Endothelial signaling by Ig-like cell adhesion molecules. Transfus. Clin. Biol. 15(1-2): 3-6
Product options: 3
30 µg in 200 µL (1)
EUR  80,00
30 µg in 200 µL (1)
EUR  80,00
for 100
tests
EUR  125,00

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