CD85a (ILT5) antibodies, human

CD85a (ILT5) antibodies, human

Clone: REA207 | Dilution: 1:11
Clone REA207 recognizes the CD85a antigen, a immunoglobulin superfamily transmembrane glycoprotein also known as leukocyte immunoglobulin-like receptor member 3 (LIR-3) or immunoglobulin-like transcript 5 (ILT5). CD85a is preferentially expressed by monocytes, macrophages, dendritic cells, and granulocytes. It provides inhibitory signals through interaction with MHC class I molecules and becomes activated upon co-ligation of CD85a and immune receptors, such as CD32 and the B cell receptor. CD85a down-regulates antigen-induced B cell–activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitory motifs.
Additional information: Clone REA207 displays negligible binding to Fc receptors.

Alternative names

LILRB3, HL9, ILT5, LILRA6, LIR-3, PIRB

Technical specifications

  • Antigen: CD85a (ILT5)
  • Clone: REA207
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: LILRB3, HL9, ILT5, LILRA6, LIR-3, PIRB
  • Distribution of antigen: macrophages, granulocytes, dendritic cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Borges, L. et al. (1997) A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules. J. Immunol. 159: 5192-5196
Product options: 14
for 30
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(1)
EUR  77,00
for 100
tests
(1)
EUR  191,00
for 30
tests
(1)
EUR  93,00
for 100
tests
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EUR  227,00
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tests
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EUR  93,00
for 100
tests
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EUR  227,00
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EUR  98,00
for 100
tests
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EUR  237,00
for 30
tests
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EUR  103,00
for 100
tests
(1)
EUR  247,00
for 30
tests
(1)
EUR  103,00
for 100
tests
(1)
EUR  247,00
for 30
tests
(1)
EUR  77,00
for 100
tests
(1)
EUR  191,00

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