CD53 antibodies, rat

CD53 antibodies, rat

Clone: REA512 | Dilution: 1:10
Clone REA512 recognizes the rat CD53 antigen, also known as Ox-44, a 43 kDa glycoprotein and a member of the tetraspanin family, which has four transmembrane domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth, and motility. CD53 is expressed on almost all hematopoietic cells such as B cells, monocytes, macrophages, neutrophils, und T cells, but not on erythrocytes and platelets.
Additional information: Clone REA512 displays negligible binding to Fc receptors.

Alternative names

Ox-44, TSPAN25

Technical specifications

  • Antigen: CD53
  • Clone: REA512
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Ox-44, TSPAN25
  • Entrez Gene ID: 24251
  • Molecular mass of antigen [kDa]: 24
  • Distribution of antigen: B cells, monocytes, macrophages, neutrophils, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
  • Selected references

    1. Bellacosa, A. (1991) The rat leukocyte antigen MRC OX-44 is a member of a new family of cell surface proteins which appear to be involved in growth regulation. Mol. Cell. Biol. 11(5): 2864-2872
    2. Tomlinson, M. G. (1993) Epitope mapping of anti-rat CD53 monoclonal antibodies. Implications for the membrane orientation of the Transmembrane 4 Superfamily. Eur. J. Immunol. 23(1): 136-140
    3. Lazo, P. A. et al. (1997) Ligation of CD53/OX44, a tetraspan antigen, induces homotypic adhesion mediated by specific cell-cell interactions. Cell. Immunol. 178(2): 132-140
Product options: 12
9 µg in 300 µL (1)
EUR  48,00
30 µg in 1 mL (1)
EUR  85,00
130-107-864

CD53-PE, rat

9 µg in 300 µL (1)
EUR  31,00
130-107-811

CD53-PE, rat

30 µg in 1 mL (1)
EUR  65,00
130-107-865

CD53-APC, rat

9 µg in 300 µL (1)
EUR  48,00
130-107-812

CD53-APC, rat

30 µg in 1 mL (1)
EUR  65,00
9 µg in 300 µL (1)
EUR  54,00
30 µg in 1 mL (1)
EUR  85,00
9 µg in 300 µL (1)
EUR  54,00
30 µg in 1 mL (1)
EUR  85,00
130-107-863

CD53-Biotin, rat

9 µg in 300 µL (1)
EUR  21,00
130-107-810

CD53-Biotin, rat

30 µg in 1 mL (1)
EUR  35,00

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