Clone REA747 recognizes the human CD45 antigen, a member of the protein tyrosine phosphatase (PTP) family, also known as the leukocyte common antigen (LCA). The CD45 molecule is a type I transmembrane protein which is required for T and B cell activation and involved in cell growth, differentiation, mitotic cycle, and oncogenic transformation. CD45 is expressed in different isoforms (CD45RA, CD45RB, CD45RC, CD45RAB, CD45RAC, CD45RBC, CD45RO, CD45R (ABC)) depending on the differentiation status of the cell. The CD45 antibody recognizes a common epitope of all CD45 isoforms.
Additional information: Clone REA747 displays negligible binding to Fc receptors.

Alternative names

Ptprc, GP180, L-CA, LY5, T200

Technical specifications

  • Antigen: CD45
  • Clone: REA747
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: Ptprc, GP180, L-CA, LY5, T200
  • Entrez Gene ID: 5788
  • Molecular mass of antigen [kDa]: 145
  • Distribution of antigen: B cells, basophils, dendritic cells, granulocytes, hematopoietic stem cells, Langerhans cells, leukocytes, lymphocytes, macrophages, mast cells, monocytes, plasma cells, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, VioBright 667, Biotin
Product options: 25
130-110-769

CD45-FITC, human

for 30
tests
(1)
EUR  60,00
130-110-631

CD45-FITC, human

for 100
tests
(1)
EUR  145,00
130-114-569

CD45-FITC, human

for 500
tests
(1)
EUR  365,00
130-110-770

CD45-PE, human

for 30
tests
(1)
EUR  80,00
130-110-632

CD45-PE, human

for 100
tests
(1)
EUR  195,00
130-110-771

CD45-APC, human

for 30
tests
(1)
EUR  80,00
130-110-633

CD45-APC, human

for 100
tests
(1)
EUR  195,00
for 30
tests
(1)
EUR  95,00
for 100
tests
(1)
EUR  230,00
for 30
tests
(1)
EUR  95,00
for 100
tests
(1)
EUR  230,00
for 30
tests
(1)
EUR  100,00
for 100
tests
(1)
EUR  240,00
for 30
tests
(1)
EUR  100,00
for 100
tests
(1)
EUR  240,00
for 30
tests
(1)
EUR  100,00
for 100
tests
(1)
EUR  240,00
for 30
tests
(1)
EUR  100,00
for 100
tests
(1)
EUR  240,00
for 30
tests
(1)
EUR  125,00
for 100
tests
(1)
EUR  300,00
for 30
tests
(1)
EUR  125,00
for 100
tests
(1)
EUR  300,00
for 30
tests
(1)
EUR  60,00
for 100
tests
(1)
EUR  145,00

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