CD253 antibodies, mouse

Clone: N2B2 | Dilution: 1:10
Clone N2B2 reacts with murine CD253, a type 2 transmembrane protein, also known as TNF-related apoptosis-inducing ligand (TRAIL), APO-2 ligand (APO-2L), or TNF ligand superfamily member 10 (TNFSF10). CD253 is expressed on a variety of cells of the innate and adaptive immune system, including natural killer (NK) cells. Often expression is induced or upregulated upon activation. CD253 can trigger apoptosis through trimerization of death receptor DR5 (TRAILR). The N2B2 antibody is reported to block CD253-mediated NK cell cytotoxicity
in vitro

Alternative names


Technical specifications

  • Antigen: CD253
  • Clone: N2B2
  • Isotype: rat IgG2aκ
  • Isotype control: Rat IgG2a – isotype control antibodies
  • Alternative names of antigen: TNFSF10, APO2L, Ly81, TL2, TRAIL
  • Entrez Gene ID: 22035
  • Molecular mass of antigen [kDa]: 33
  • Distribution of antigen: B cells, dendritic cells, gut, kidney, lung, monocytes, NK cells, spleen, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, VioBlue, Biotin, FITC
Product options: 5
30 µg in 1 mL (1)
EUR  35,00

CD253-PE, mouse

30 µg in 1 mL (1)
EUR  65,00

CD253-APC, mouse

30 µg in 1 mL (1)
EUR  65,00
30 µg in 1 mL (1)
EUR  80,00
30 µg in 1 mL (1)
EUR  35,00

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