CD22 antibodies, mouse

CD22 antibodies, mouse

Clone: Cy34.1 | Dilution: 1:50
The monoclonal antibody Cy34.1 recognizes the 150 kDa B cell–restricted glycoprotein CD22 on mice strains having the Lyb-8.2 alloantigen, e.g., A, BALB/c, CBA, C3H/He, C57BL, C57L, C58, SJL, SWR. Lyb-8.2 is expressed at mature levels on all B cell subsets. In bone marrow, CD22 is not detectable on pro–B cells, pre–B cells, and emerging IgM
+
B cells. CD22 plays a strong role in cell interactions and B cell activation.

Alternative names

Lyb-8, BL-CAM, SIGLEC-2

Technical specifications

  • Antigen: CD22
  • Clone: Cy34.1
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: Lyb-8, BL-CAM, SIGLEC-2
  • Entrez Gene ID: 12483
  • Molecular mass of antigen [kDa]: 94
  • Distribution of antigen: B cells, basophils, dendritic cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE-Vio770
  • Selected references

    1. Erickson, L. D. et al. (1996) Differential expression of CD22 (Lyb8) on murine B cells. Immunogenetics 8(7): 1121-1129
    2. Symington, F. W. et al. (1982) Lyb-8.2: A new B cell antigen defined and characterized with a monoclonal antibody. Immunogenetics 16(5): 381-391
    3. Law, C. L. et al. (1994) Regulation of lymphocyte activation by the cell-surface molecule CD22. Immunol. Today 15(9): 442-449
Product options: 1
30 µg in 200 µL (1)
EUR  85,00

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