CD16 antibodies, human

CD16 antibodies, human

Clone: VEP13 | Dilution: 1:50
CD16 is a 50–80 kDa glycoprotein that is expressed in two different isoforms. The transmembrane form is found on human NK cells, macrophages, and mast cells, while the glycosylphosphatidylinositol (GPI)-linked form is present on neutrophils.
The human CD16 antigen is a low-affinity receptor for aggregated IgG. The transmembrane form plays a role in signal transduction, NK cell activation, and antibody-dependent cellular cytotoxicity. Clone VEP13 recognizes both the extracellular domain of the transmembrane form as well as the GPI-linked form of the human CD16 antigen. CD16 is expressed on the majority of rhesus monkey NK cells and on a subset of monocytes but not on granulocytes.

Alternative names


Technical specifications

  • Antigen: CD16
  • Clone: VEP13
  • Isotype: mouse IgMκ
  • Isotype control: Mouse IgM – isotype control antibodies
  • Alternative names of antigen: FcγRIIIA, FcγRIIIB, FcR-10, IGFR3, IMD20
  • Entrez Gene ID: 2214
  • Molecular mass of antigen [kDa]: 20-27
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    cynomolgus monkey (
    Macaca fascicularis
  • Distribution of antigen: eosinophils, granulocytes, macrophages, mast cells, monocytes, myeloid cells, neutrophils, NK cells, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: Biotin
  • Selected references

    1. Schlaepfer, E. et al. (2008)
      Anti-HIV activity mediated by natural killer and CD8
      cells after toll-like receptor 7/8 triggering.
      PLoS One 3(4): e1999
Product options: 2
for 30
EUR  62,00
for 100
EUR  149,00

Related products

3 products available