CD122 (IL-2Rβ) antibodies, mouse

CD122 (IL-2Rβ) antibodies, mouse

Clone: TM-β1 | Dilution: 1:10
The monoclonal antibody TM-ß1 recognizes the murine CD122 70–75 kDa cell surface glycoprotein, also known as interleukin-2 receptor beta chain (IL-2Rβ). CD122 is constitutively expressed on mouse NK cells and at a lower level on subsets of T cells, B cells, monocytes, and macrophages. CD122 can associate with the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25), resulting in intermediate or high affinity IL-2 receptor complexes. CD122 expression levels can be upregulated by activation. The TM-β1 antibody interferes with binding of IL-2 to the receptor and can be used to deplete CD122
+
cells.

Alternative names

IL2RB, IL-15Rbeta, Il-2/15Rbeta, Il-2Rbeta, p70, IL-2Rβ

Technical specifications

  • Antigen: CD122 (IL-2Rβ)
  • Clone: TM-β1
  • Isotype: rat IgG2bκ
  • Isotype control: Rat IgG2b – isotype control antibodies
  • Alternative names of antigen: IL2RB, IL-15Rbeta, Il-2/15Rbeta, Il-2Rbeta, p70, IL-2Rβ
  • Entrez Gene ID: 16185
  • Molecular mass of antigen [kDa]: 58
  • Distribution of antigen: B cells, macrophages, monocytes, NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, APC-Vio770, Biotin, FITC
  • Selected references

    1. Tanaka, T. et al. (1991) A novel monoclonal antibody against murine IL-2 receptor beta-chain. Characterization of receptor expression in normal lymphoid cells and EL- 4 J. Immunol. 147: 2222-2228
Product options: 8
30 µg in 1 mL (1)
EUR  36,00
30 µg in 1 mL (1)
EUR  67,00
30 µg in 1 mL (1)
EUR  67,00
9 µg in 300 µL (1)
EUR  56,00
30 µg in 1 mL (1)
EUR  88,00
9 µg in 300 µL (1)
EUR  56,00
30 µg in 1 mL (1)
EUR  88,00
30 µg in 1 mL (1)
EUR  36,00

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