Anti-TCRγ/δ antibodies, human

Anti-TCRγ/δ antibodies, human

Clone: REA591 | Dilution: 1:50
Clone REA591 recognizes the human TCRγ/δ antigen. The T cell receptor is a heterodimeric glycoprotein associated with the CD3 antigen. It consists of an α and a β chain (TCRα/β) or a γ and a δ chain (TCRγ/δ). The γ and δ TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. The γ chain forms either disulfide-linked or non-disulfide–linked heterodimers with the δ-subunit. The γ/δ T cell receptor is present on a subset of T lymphocytes in peripheral blood. TCRγ/δ is involved in the antigen recognition of tumor-associated antigens or bacterial antigens presented by MHC class I molecules.
Additional information: Clone REA591 displays negligible binding to Fc receptors.

Alternative names

TCRgd

Technical specifications

  • Antigen: TCRγ/δ
  • Clone: REA591
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: TCRgd
  • Entrez Gene ID: 6965
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Airoldi, I. et al. (2015)
      γδ T-cell reconstitution after HLA-haploidentical hematopoietic transplantation depleted of TCR-αβ
      +
      /CD19
      +
      lymphocytes.
      Blood 125(15): 2349-2358
    2. Bonneville, M. et al. (2010) Gammadelta T cell effector functions: a blend of innate programming and acquired plasticity. Nat. Rev. Immunol. 10(7): 467-478
    3. Wiest, D. L. (2016) Development of γδ T cells, the special-force soldiers of the immune system. Methods Mol. Biol. 1323: 23-32
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EUR  240,00
for 30
tests
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EUR  100,00
for 100
tests
(1)
EUR  240,00
for 30
tests
(1)
EUR  100,00
for 100
tests
(1)
EUR  240,00
for 30
tests
(1)
EUR  75,00
for 100
tests
(1)
EUR  185,00

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