Anti-TCR Vβ14 antibodies, human

Anti-TCR Vβ14 antibodies, human

Clone: REA557 | Dilution: 1:11
Clone REA557 recognizes the human Vβ14 T cell receptor (TCR Vβ14). The TCR is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains. TCR Vβ14 is expressed on a subset of α/β T cells.
Additional information: Clone REA557 displays negligible binding to Fc receptors

Alternative names

TCR Vbeta14

Technical specifications

  • Antigen: TCR Vβ14
  • Clone: REA557
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: TCR Vbeta14
  • Entrez Gene ID: 6957
  • Molecular mass of antigen [kDa]: 13
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, APC-Vio770, Biotin
  • Selected references

    1. Robinson, M. A. et al. (1989) Allelic sequence variations in the hypervariable region of a T-cell receptor beta chain: correlation with restriction fragment length polymorphism in human families and populations. Proc. Natl. Acad. Sci. U.S.A. 86: 9422-9426
    2. Kurt, R. A. et al. (2000)
      TCR v(beta) usage and clonality of T cells isolated from progressing and rejected tumor sites before and after
      in vitro
      culture.
      Int. Immunol. 12(5): 639-646
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