Anti-KIR2D antibodies, human

Anti-KIR2D antibodies, human

Clone: NKVFS1 | Dilution: 1:50
The Anti-KIR2D antibody recognizes the killer immunoglobulin-like receptor (KIR) 2D subtype on human and non-human primate cells. It recognizes all KIRs bearing two extracellular Ig-like domains, and also both activating and inhibitory KIR isoforms (KIR2DS and KIR2DL, respectively). KIRs are expressed on CD56
natural killer (NK) cells and a subset of CD8
T cells. KIRs contribute to the regulation of NK cell-mediated cytotoxicity. They are monomeric receptors possessing high allelic polymorphism with either two or three Ig-like extracellular domains (KIR2D or KIR3D, respectively). According to the length of their cytoplasmic tail, KIRs can be subdivided in long-tailed inhibitory KIRs (KIR2DL or KIR3DL) and short-tailed activating KIRs (KIR2DS or KIR3DS).

Alternative names


Technical specifications

  • Antigen: KIR2D
  • Clone: NKVFS1
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: CD158A
  • Entrez Gene ID: 3806, 100132285, 3808, 3809, 3810, 3802, 3803, 3804, 3805, 57292
  • Molecular mass of antigen [kDa]: 31-39
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
  • Distribution of antigen: NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE
  • Selected references

    1. Hsu, K. et al. (2002) The killer cell immunoglobin-like (KIR) genomic region: gene-order, haplotypes and allelic polymorphism. Immunol. Rev. 190: 40-52
    2. Selvakumar, A. et al. (1997) Polymorphism and domain variability of human killer cell inhibitory receptors. Immunol. Rev. 155: 183-196
  • Customer reports and application notes

Product options: 2
for 30
EUR  95,00
for 100
EUR  225,00

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