Anti-HLA-A2 A28 antibodies, human

Anti-HLA-A2 A28 antibodies, human

Clone: REA142 | Dilution: 1:11
Clone REA142 recognizes HLA A2 and HLA A28, class I human leukocyte antigens (HLA). Expressed on the surface of most nucleated cells, class I molecules are heterodimeric molecules and consist of a type I integral membrane α heavy chain and soluble β2 microglobulin protein. The extracellular region of the heavy chain further consists of 3 domains, of which one comprises the peptide binding groove. Antigens binding to class I molecules are 8–10 amino acids long and play an important role in recognition of the virus infected and malignant cells by cytotoxic T lymphocytes (CTLs). In addition, class I molecules interact with NK cell receptors to modulate the activity of NK cells.
Additional information: Clone REA142 displays negligible binding to Fc receptors.

Alternative names

HLA-A

Technical specifications

  • Antigen: HLA-A2, A28
  • Clone: REA142
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: HLA-A
  • Entrez Gene ID: 3105
  • Molecular mass of antigen [kDa]: 38
  • Distribution of antigen: B cells, T cells, dendritic cells, epithelial cells, lymphocytes, granulocytes, leukocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Hewitt, E. W. et al. (2003) The MHC class I antigen presentation pathway: strategies for viral immune evasion. Immunology 110(2): 163-169
Product options: 18
for 30
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for 100
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EUR  190,00
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EUR  95,00
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EUR  225,00
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EUR  95,00
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tests
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EUR  225,00
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tests
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EUR  95,00
for 100
tests
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EUR  230,00
for 30
tests
(1)
EUR  95,00
for 100
tests
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EUR  230,00
for 30
tests
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EUR  100,00
for 100
tests
(1)
EUR  240,00
for 30
tests
(1)
EUR  100,00
for 100
tests
(1)
EUR  240,00
for 30
tests
(1)
EUR  100,00
for 100
tests
(1)
EUR  240,00
for 30
tests
(1)
EUR  80,00
for 100
tests
(1)
EUR  190,00

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