Anti-CCL7 (MCP-3) antibodies, human

Anti-CCL7 (MCP-3) antibodies, human

Clone: REA328 | Dilution: 1:10
Clone REA328 recognizes the human C-C motif chemokine 7 (CCL7) antigen, an inflammatory cytokine also known as monocyte chemotactic protein 3 (MCP-3). Human CCL7 is secreted by several tumor cell lines and macrophages as a precursor protein containing 99 amino acids, including an aminoterminal hydrophobic signal sequence. It is one of the most broadly active chemokines, potently inducing chemotaxis of monocytes, basophils, eosinophils, and lymphocytes, as well as degranulation of basophils, eosinophils, and monocytes.
Additional information: Clone REA328 displays negligible binding to Fc receptors.

Alternative names

FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7

Technical specifications

  • Antigen: CCL7 (MCP-3)
  • Clone: REA328
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7
  • Entrez Gene ID: 6354
  • Molecular mass of antigen [kDa]: 9
  • Distribution of antigen: macrophages, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC
  • Selected references

    1. Tsou, C. L. et al. (2007) Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites. J. Clin. Invest. 117(4): 902-909
    2. Opdenakker, G. et al. (1993) Human monocyte chemotactic protein-3 (MCP-3): molecular cloning of the cDNA and comparison with other chemokines. Biochem. Biophys. Res. Commun. 191(2): 535-542
    3. Menten, P. et al. (2001) Monocyte chemotactic protein-3. Eur. Cytokine Netw. 12(4): 554-560
Product options: 4
for 30
tests
(1)
EUR  90,00
for 100
tests
(1)
EUR  220,00
for 30
tests
(1)
EUR  90,00
for 100
tests
(1)
EUR  220,00

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