Human FGF-10

Human FGF-10

FGF-10 stands for fibroblast growth factor 10. Human FGF-10 is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays.

Applications

Human FGF-10 can be used for a variety of applications, including:
  • Induction of proliferation and differentiation of epithelial cells.
  • Investigation of FGFR 2 signaling.
  • ES/iPS cell culture.

Alternative names

KGF-2

Background information

Fibroblast growth factor 10 (FGF-10) belongs to the FGF family, which is involved in embryogenesis and adult tissue development and regeneration. The function of FGF-10 partially overlaps with the one of other FGF members such as FGF-7. It is expressed in mesenchymal cells especially in lungs, and signals via FGFR 2. FGF-10 influences the development of several tissues including lungs and adipose tissues, and its activity is inhibited by SHH and BMP-4. Human FGF-10 shares 93% amino acid sequence mouse FGF-10.

Quality description

Research-grade
cytokines are suitable for a wide variety of cell culture applications. They are sterile-filtered prior to lyophilization. Generally, endotoxin levels are <0.1 ng/μg (<1 EU/μg), and purities are >95%. The biological activity is tested in appropriate bioassays.

Biological activity

  • Proliferation of BaF3 cells
  • research grade: ≥ 2×
    10
    6
    U/mg
Product options: 2
E. coli
25 µg
EUR  190,00
E. coli
100 µg
EUR  515,00