Clone:
REA867
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
E-NPP 1, Ly-41, PC-1

Specifications for ENPP1 Antibody, anti-mouse, REAfinity™

Overview

Clone REA867 recognizes the mouse ENPP1 type II transmembrane glycoprotein, also known as PC-1 (Plasma-cell membrane glycoprotein PC-1) or Ly-41. ENPP1 is mainly found on the surface of antibody-secreting plasma cells and on some subsets of nonlymphoid cells having a 5'-nucleotide phosphodiesterase activity. It is suggested, that ENPP1 plays a role in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of insulin signaling.
Additional information: Clone REA867 displays negligible binding to Fc receptors.

Alternative names

E-NPP 1, Ly-41, PC-1

Detailed product information

Technical specifications

CloneREA867
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hosthuman cell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenENPP1
Alternative names of antigenE-NPP 1, Ly-41, PC-1
Molecular mass of antigen [kDa]103
Distribution of antigenplasma cells
Entrez Gene ID18605
RRIDAB_2726524, AB_2726594, AB_2726525, AB_2726595, AB_2726526, AB_2726596, AB_2726527, AB_2726597, AB_2726528, AB_2726592, AB_2726523, AB_2726593

Resources for ENPP1 Antibody, anti-mouse, REAfinity™

Certificates

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References for ENPP1 Antibody, anti-mouse, REAfinity™

Publications

  1. van Driel, I. R. et al. (1985) Murine plasma cell membrane antigen PC-1: molecular cloning of cDNA and analysis of expression. Proc. Natl. Acad. Sci. U.S.A. 82(24): 8619-8623
  2. Belli, S. I. et al. (1993) Identification and characterization of a soluble form of the plasma cell membrane glycoprotein PC-1 (5'-nucleotide phosphodiesterase). Eur. J. Biochem. 217(1): 421-428
  3. Zhou, H. H. et al. (2009)
    Suppression of PC-1/ENPP-1 expression improves insulin sensitivity
    in vitro
    and
    in vivo
    .
    Eur. J. Pharmacol. 616(1-3): 346-352

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