Type of antibody:
Primary antibodies, Recombinant antibodies
recombinant human IgG1
Alternative names:
JAM-A, JAM-1, F11

Specifications for CD321 (JAM1) Antibody, anti-mouse, REAfinity™


Clone REA854 recognizes the mouse CD321 antigen, a type I transmembrane glycoprotein containing two extracellular immunoglobulin-like domains. CD321 is a receptor molecule also known as junctional adhesion molecule 1 (JAM1) and is expressed on some epithelial cells, macrophages, and dendritic cells. It is involved in regulating monocyte transmigration as well as in the organization and function of antigen-presenting cells. Furthermore, CD321 acts as a ligand for the integrin LFA1, which plays a role in leukocyte transmigration.
Additional information: Clone REA854 displays negligible binding to Fc receptors.

Alternative names

JAM-A, JAM-1, F11

Detailed product information

Technical specifications

Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hosthuman cell line
Type of antibodyPrimary antibodies, Recombinant antibodies
AntigenCD321 (JAM1)
Alternative names of antigenJAM-A, JAM-1, F11
Molecular mass of antigen [kDa]30
Distribution of antigenepithelial cells, macrophages, dendritic cells
Entrez Gene ID16456
RRIDAB_2725838, AB_2725857, AB_2725839, AB_2725858, AB_2725840, AB_2725855, AB_2725837, AB_2725856

Resources for CD321 (JAM1) Antibody, anti-mouse, REAfinity™


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References for CD321 (JAM1) Antibody, anti-mouse, REAfinity™


  1. Malergue, F. et al. (1998) A novel immunoglobulin superfamily junctional molecule expressed by antigen presenting cells, endothelial cells and platelets. Mol. Immunol. 35(17): 1111-1119
  2. Martìn-Padura, I. et al. (1998) Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J. Cell Biol. 142(1): 117-127

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