In the study published in Cell, the group of Ali Ertürk from the Institute for Tissue Engineering and Regenerative Medicine (iTERM), Helmholtz Zentrum München, Germany used the UltraMicroscope Blaze to identify hundreds of small metastases throughout the mouse body.
These disseminated tumor cells were otherwise undetectable by other methods. The UltraMicroscope Blaze also enabled them to see exactly which metastasis was targeted by a drug candidate and which one was missed.
According to the researchers, this method could significantly increase the success rate of cancer drug candidates.
Pan, C. et al. (2019) Cell 179: 1661–1676.e19. (PMID:31835038).